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Poliklinika Analiza
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Genetic test for caffeine intolerance

This test provides insight into genetic predispositions that affect the breakdown of caffeine, a key ingredient in coffee. With the help of this test, it is possible to better understand how the body responds to caffeine and how to adapt coffee consumption to individual needs and preferences.

ABOUT THE GENES

The individual rate of caffeine breakdown varies between people because of genetic differences. These variations affect the speed at which the body breaks down and eliminates caffeine.

The CYP1A2 gene plays a key role in caffeine metabolism in the human body. This gene encodes the enzyme responsible for breaking down caffeine in the liver. Variations in the CYP1A2 gene significantly affect the speed at which individuals metabolise caffeine.

There are two main gene variants, one referred to as fast and the other as slow. People with the fast variant have greater enzyme activity, meaning that caffeine remains in their body for a shorter time, reducing the duration and intensity of its effects. On the other hand, people with the slow variant have reduced enzyme activity, leading to slower caffeine metabolism and longer retention in the body. This can increase the risk of negative effects of caffeine, such as insomnia, nervousness or increased blood pressure, even when moderate amounts are consumed.

Split

Dugopolje

Zadar 

Šibenik

021 688 888

Zagreb

Varaždin

01 2099 880

Rijeka

051 309 309

PREPARATION

It is recommended that no food or drink (except water) be consumed and that teeth not be brushed for at least an hour immediately before testing.

SAMPLE COLLECTION PROCEDURE

The sample collection procedure is simple and quick. The inside of the cheek needs to be rubbed with a special sterile swab for 30-60 seconds.

ANALYSIS

People who break down caffeine more slowly may feel nervous or irritable after consuming caffeine. However, this is not always necessarily the case. Even if they do not experience immediate symptoms, increased caffeine intake may negatively affect their blood pressure and heart health. Knowing individual variations in the CYP1A2 gene can therefore be useful for adjusting caffeine consumption to optimise its positive effects and minimise negative ones. The results of the Caffeine Intolerance genetic test provide important guidance on adapting caffeine consumption to genetic predispositions. Alongside general guidance, information is provided on the amounts of caffeine in different foods. Examples of foods and their caffeine content help provide a better understanding of how much caffeine comes from different sources. It is therefore advisable to read product labels carefully and adjust caffeine intake according to the recommendations obtained through the genetic test.

Genetic test for caffeine intolerance
60.00€

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