Sedimentation

DESCRIPTION:
If blood containing an anticoagulant is left to stand in a vertically positioned pipette, red blood cells will gradually begin to settle to the bottom. The rate at which these cells settle is sensitive to the body’s response index to injury or disease, such as leukocytosis or fever. The mechanism of accelerated sedimentation is primarily cell aggregation, after which large aggregates settle more rapidly. Such cell aggregation is associated with increased concentration of globulins and fibrinogen in the blood or decreased albumin levels in the blood. A normal sedimentation rate does not exclude the possibility of disease, but an accelerated sedimentation rate is an indicator for further testing. The significance of sedimentation is that it indicates the possible presence of organic disease or is used to monitor the course of disease.

DETERMINATION:
Recommended method and/or procedure I: Modified Westergren method (ICSH) Sample for analysis is whole blood (Na-citrate)

RESULTS:
Reference interval depends on sex and age. Reference interval is displayed on each validated result.

3.20